Klinik und Poliklinik für Anästhesiologie und Intensivtherapie

Publikationen 2018


Abe T, Madotto F, Pham T, Nagata I, Uchida M, Tamiya N, Kurahashi K, Bellani G, Laffey JG; LUNG-SAFE Investigators and the ESICM Trials Group. Epidemiology and patterns of tracheostomy practice in patients with acute respiratory distress syndrome in ICUs across 50 countries. Crit Care. 2018 Aug 17;22(1):195.

Armbruster A, Neumann E, Kötter V, Hermanns H, Werdehausen R, Eulenburg V. The GlyT1 Inhibitor Bitopertin Ameliorates Allodynia and Hyperalgesia in Animal Models of Neuropathic and Inflammatory Pain. Front Mol Neurosci 2018; 10: 438.

Ball L, Hemmes SNT, Serpa Neto A, Bluth T, Canet J, Hiesmayr M, Hollmann MW, Mills GH, Vidal Melo MF, Putensen C, Schmid W, Severgnini P, Wrigge H, Gama de Abreu M, Schultz MJ, Pelosi P; LAS VEGAS investigators; PROVE Network; Clinical Trial Network of the European Society of Anaesthesiology. Intraoperative ventilation settings and their associations with postoperative pulmonary complications in obese patients. Br J Anaesth. 2018 Oct;121(4):899-908.

Becke K, Eich C, Höhne C, Jöhr M, Machotta A, Schreiber M, Sümpelmann R. Choosing Wisely in pediatric anesthesia: An interpretation from the German Scientific Working Group of Paediatric Anaesthesia (WAKKA). Paediatr Anaesth. 2018 Jul;28(7):588-596. doi: 10.1111/pan.13383.

Bein T, Wrigge H. Airway pressure release ventilation (APRV): do good things come to those who can wait? J Thorac Dis 2018; 10(2): 667-669.

Bercker S, Winkelmann T, Busch T, Laudi S, Lindner D, Meixensberger J. Hydroxyethyl starch for volume expansion after subarachnoid haemorrhage and renal function: Results of a retrospective analysis. PLoS One 2018; 13(2): e0192832.

Blecha S, Dodoo-Schittko F, Brandstetter S, Brandl M, Dittmar M, Graf BM, Karagiannidis C, Apfelbacher C, Bein T; DACAPO Study Group (Jahn N, Bercker S). Quality of inter-hospital transportation in 431 transport survivor patients suffering from acute respiratory distress syndrome referred to specialist centers. Ann Intensive Care 2018; 8(1): 5.

Both CP, Thomas J, Bühler PK, Schmitz A, Weiss M, Piegeler T. Factors associated with intravenous lidocaine in pediatric patients undergoing laparoscopic appendectomy - a retrospective, single-centre experience. BMC Anesthesiol. 2018 Jul 18;18(1):88.

Boyle A, Madotto F, Laffey JG, Bellani G, Pham T, Pesenti A, Thompson BT, O'Kane CM, Deane AM, McAuley DF; LUNG SAFE Investigators; ESICM Trials Group. Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database. Crit Care. 2018 Oct 27;22(1):268.

Burau D, Petroff D, Simon P, Ehmann L, Weiser C, Dorn C, Kratzer A, Wrigge H, Kloft C. Drug combinations and impact of experimental conditions on relative recovery in in vitro microdialysis investigations. Eur J Pharm Sci. 2018 Oct 31;127:252-260.

Cortegiani A, Madotto F, Gregoretti C, Bellani G, Laffey JG, Pham T, Van Haren F, Giarratano A, Antonelli M, Pesenti A, Grasselli G; LUNG SAFE Investigators and the ESICM Trials Group. Immunocompromised patients with acute respiratory distress syndrome: secondary analysis of the LUNG SAFE database. Crit Care. 2018 Jun 12;22(1):157.

Dorn C, Kratzer A, Liebchen U, Schleibinger M, Murschhauser A, Schlossmann J, Kees F, Simon P, Kees MG. Impact of Experimental Variables on the Protein Binding of Tigecycline in Human Plasma as Determined by Ultrafiltration. J Pharm Sci 2018; 107(2): 739-744.

Dodoo-Schittko F, Brandstetter S, Brandl M, Blecha S, Quintel M, Weber-Carstens S, Kluge S, Kirschning T, Muders T, Bercker S, Ellger B, Arndt C, Meybohm P, Adamzik M, Goldmann A, Karagiannidis C, Bein T, Apfelbacher C, DACAPO Study Group. German-wide prospective DACAPO cohort of survivors of the acute respiratory distress syndrome (ARDS): a cohort profile. BMJ Open 2018; 8(4): e019342.

Eulenburg V, Knop G, Sedmak T, Schuster S, Hauf K, Schneider J, Feigenspan A, Joachimsthaler A, Brandstätter JH. GlyT1 determines the glycinergic phenotype of amacrine cells in the mouse retina. Brain Struct Funct. 2018 Sep;223(7):3251-3266.

Fichtner, Falk; Mörer, Onnen; Laudi, Sven; Weber-Carstens, Steffen; Nothacker, Monika; Kaisers, Udo. Clinical practice guideline: Mechanical ventilation and extracorporeal membrane oxygenation in acute respiratory insufficiency. Dtsch Arztebl Int 2018; 115(50): 840-7

Flenner F, Arlt N, Nasib M, Schobesberger S, Koch T, Ravens U, Friedrich F, Nikolaev V, Christ T, Stehr SN. In Vitro Negative Inotropic Effect of Low Concentrations of Bupivacaine Relates to Diminished Ca2+ Sensitivity but not to Ca2+ Handling or β-Adrenoceptor Signaling. Anesthesiology 2018; doi: 10.1097/ALN.0000000000002180. [Epub ahead of print]

Girrbach FF, Bernhard M, Hammer N, Bercker S. Intranasale Medikamentengabe – Technik und Indikationen. Notfall Rettungsmed 2018; 21(2): 120-128.

Girrbach FF, Hilbig F, Michael M, Bernhard M. [Systematic analysis of airway registries in emergency medicine]. Anaesthesist. 2018 Sep;67(9):664-673. German.

Gille J, Schmidt T, Dragu A, Emich D, Hilbert-Carius P, Kremer T, Raff T, Reichelt B, Siafliakis A, Siemers F, Steen M, Struck MF. Electrical injury – a dual center analysis of patient characteristics, therapeutic specifics and outcome predictors. Scand J Trauma Resusc Emerg Med. 2018 May 31;26(1):43.

Hartog CS, Hoffmann F, Mikolajetz A, Schröder S, Michalsen A, Dey K, Riessen R, Jaschinski U, Weiss M, Ragaller M, Bercker S, Briegel J, Spies C, Schwarzkopf D; SepNet Critical Care Trials Group – Ethicus II Studiengruppe. [Non-beneficial therapy and emotional exhaustion in end-of-life care : Results of a survey among intensive care unit personnel]. Anaesthesist. 2018 Nov;67(11):850-858.

Hempel G, Simon P, Salz P, Wrigge H. [Respiratory Failure: Innovations in Diagnostics and Therapy]. Anasthesiol Intensivmed Notfallmed Schmerzther 2018; 53(2): 126-140.

Hempel G, Schulze G, Wirtz H, Wrigge H. Electrical Impedance Tomography for Confirmation of Lung Isolation during One-lung Ventilation. Anesthesiology 2018; doi: 10.1097/ALN.0000000000002189. [Epub ahead of print]

Hermanns H, Werdehausen R, Hollmann MW, Stevens MF. Assessment of skin temperature during regional anaesthesia-What the anaesthesiologist should know. Acta Anaesthesiol Scand. 2018 Oct;62(9):1280-1289. doi: 10.1111/aas.13176. Epub 2018 Jun 25. Review.

Hilbert-Carius P, Struck MF, Hofer V, Hinkelbein J, Wurmb T, Bernhard M, Hossfeld B. [Transport of ventilated emergency patients from the air rescue service to the hospital destination (HOVER study) : Results of an online survey]. Anaesthesist. 2018 Nov;67(11):821-828. doi: 10.1007/s00101-018-0484-8. Epub 2018 Sep 11. German.

Hilbert-Carius P, Schwarzkopf D, Reinhart K, Hartog CS, Lefering R, Bernhard M, Struck MF. Synthetic colloid resuscitation in severely injured patients: analysis of a nationwide trauma registry (TraumaRegister DGU). Sci Rep. 2018 Aug 1;8(1):11567.

Huber SE, Zoicas I, Reichel M, Mühle C, Büttner C, Ekici AB, Eulenburg V, Lenz B, Kornhuber J, Müller CP. Prenatal androgen receptor activation determines adult alcohol and water drinking in a sex-specific way. Addict Biol. 2018 May;23(3):904-920.

Kaiser T, Finstermeier K, Häntzsch M, Faucheux S, Kaase M, Eckmanns T, Bercker S, Kaisers UX, Lippmann N, Rodloff AC, Thiery J, Lübbert C. Stalking a lethal superbug by whole-genome sequencing and phylogenetics: Influence on unraveling a major hospital outbreak of carbapenem-resistant Klebsiella pneumoniae. Am J Infect Control 2018; 46(1): 54-59.

Kaczmarek-Hajek K, Zhang J, Kopp R, Grosche A, Rissiek B, Saul A, Bruzzone S, Engel T, Jooss T, Krautloher A, Schuster S, Magnus T, Stadelmann C, Sirko S, Koch-Nolte F, Eulenburg V, Nicke A. Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody. Elife. 2018 Aug 3;7. pii: e36217.

Laffey JG, Bellani G, Pham T, Fan E, Madotto F, Bajwa EK, Brochard L, Clarkson K, Esteban A, Gattinoni L, van Haren F, Heunks LM, Kurahashi K, Laake JH, Larsson A, McAuley DF, McNamee L, Nin N, Qiu H, Ranieri M, Rubenfeld GD, Thompson BT, Wrigge H, Slutsky AS, Pesenti A; LUNG SAFE Investigators; ESICM Trials Group (Wrigge H, Reske AW, Simon P). Correction to: Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study. Intensive Care Med. 2018 Jan;44(1):157-165.

Lübbert C, Wendt S, Sander C, Beeskow A, Becker-Rux D. Intracranial hypertension and vasculitic infarction in a patient with severe cerebral melioidosis. Lancet Infect Dis. 2018 Oct;18(10):1160.

Madotto F, Pham T, Bellani G, Bos LD, Simonis FD, Fan E, Artigas A, Brochard L, Schultz MJ, Laffey JG, LUNG SAFE Investigators and the ESICM Trials Group (Wrigge H, Reske AW, Simon P). Resolved versus confirmed ARDS after 24 h: insights from the LUNG SAFE study. Intensive Care Med 2018; doi: 10.1007/s00134-018-5152-6.

Meybohm P, Kohlhaas M, Stoppe C, Gruenewald M, Renner J, Bein B, Albrecht M, Cremer J, Coburn M, Schaelte G, Boening A, Niemann B, Sander M, Roesner J, Kletzin F, Mutlak H, Westphal S, Laufenberg-Feldmann R, Ferner M, Brandes IF, Bauer M, Stehr SN, Kortgen A, Wittmann M, Baumgarten G, Meyer-Treschan T, Kienbaum P, Heringlake M, Schoen J, Treskatsch S, Smul T, Wolwender E, Schilling T, Fuernau G, Bogatsch H, Brosteanu O, Hasenclever D, Zacharowski K, RIPHeart (Remote Ischemic Preconditioning for Heart Surgery) Study Collaborators. RIPHeart (Remote Ischemic Preconditioning for Heart Surgery) Study: Myocardial Dysfunction, Postoperative Neurocognitive Dysfunction, and 1 Year Follow-Up. J Am Heart Assoc 2018;7(7); e008077.

Mielenz D, Reichel M, Jia T, Quinlan EB, Stöckl T, Mettang M, Zilske D, Kirmizi-Alsan E, Schönberger P, Praetner M, Huber SE, Amato D, Schwarz M, Purohit P, Brachs S, Spranger J, Hess A, Büttner C, Ekici AB, Perez-Branguli F, Winner B, Rauschenberger V, Banaschewski T, Bokde ALW, Büchel C, Conrod PJ, Desrivières S, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Martinot JL, Lemaitre H, Nees F, Paus T, Smolka MN; IMAGEN Consortium, Schambony A, Bäuerle T, Eulenburg V, Alzheimer C, Lourdusamy A, Schumann G, Müller CP. EFhd2/Swiprosin-1 is a common genetic determinator for sensation-seeking/low anxiety and alcohol addiction. Mol Psychiatry. 2018 May;23(5):1303-1319.

Moulla Y, Lyros O, Blüher M, Simon P, Dietrich A. Feasibility and Safety of Bariatric Surgery in High-Risk Patients: A Single-Center Experience. J Obes 2018; 9: 7498258. doi: 10.1155/2018/7498258. eCollection 2018.

Motta-Ribeiro GC, Jandre FC, Wrigge H, Giannella-Neto A. Generalized estimation of the ventilatory distribution from the multiple-breath washout: a bench evaluation study. Biomed Eng Online 2018; 17(1): 3.

Muessig JM, Nia AM, Masyuk M, Lauten A, Sacher AL, Brenner T, Franz M, Bloos F, Ebelt H, Schaller SJ, Fuest K, Rabe C, Dieck T, Steiner S, Graf T, Jánosi RA, Meybohm P, Simon P, Utzolino S, Rahmel T, Barth E, Schuster M, Kelm M, Jung C. Clinical Frailty Scale (CFS) reliably stratifies octogenarians in German ICUs: a multicentre prospective cohort study. BMC Geriatr. 2018 Jul 13;18(1):162.

Neto AS, da Costa LGV, Hemmes SNT, Canet J, Hedenstierna G, Jaber S, Hiesmayr M, Hollmann MW, Mills GH, Vidal Melo MF, Pearse R, Putensen C, Schmid W, Severgnini P, Wrigge H, Gama de Abreu M, Pelosi P, Schultz MJ; LAS VEGAS.The LAS VEGAS risk score for prediction of postoperative pulmonary complications: An observational study. Eur J Anaesthesiol. 2018 Sep;35(9):691-701.

Petroff D, Simon P, Wrigge H. Response to: 'Positive end-expiratory pressure in obese patients during general anaesthesia. The role of intra-abdominal pressure'. Br J Anaesth 2018; 120(2): 410-411.

Pham T, Serpa Neto A, Pelosi P, …. Wrigge H,…. Jovanovic B, Surbatovic M, Veljovic M; LUNG SAFE Investigators and the ESICM Trials Group (Wrigge H, Reske AW, Simon P). Outcomes of Patients Presenting with Mild Acute Respiratory Distress Syndrome: Insights from the LUNG SAFE Study. Anesthesiology. 2018 Nov 27. doi: 10.1097/ALN.0000000000002508. [Epub ahead of print]

Pickerodt PA, Kronfeldt S, Russ M, Gonzalez-Lopez A, Lother P, Steiner E, Vorbrodt K, Busch T, Boemke W, Francis RCE, Swenson ER. Carbonic anhydrase is not a relevant nitrite reductase or nitrous anhydrase in the lung. J Physiol – London 2018; doi: 10.1113/JP275894. [Epub ahead of print]

Piegeler T, Stehr SN, Pfirrmann D, Knödler M, Lordick F, Mehnert A, Selig L, Weimann A, Mehdorn M, Gockel I, Simon P. [Special situations of preconditioning and prehabilitation in oncological visceral surgery]. Chirurg. 2018 Nov;89(11):903-908.

Piegeler T, Werdehausen R. [Systemic effects of amide-linked local anesthetics : Old drugs, new magic bullets?]. Anaesthesist. 2018 Jul;67(7):525-528.

Schnoor J, Busch T, Turemuratov N, Merkenschlager A. Pre-anesthetic assessment with three core questions for the detection of obstructive sleep apnea in childhood: An observational study. BMC Anesthesiol 2018; 18(1): 25.

Schulz D, Morschel J, Schuster S, Eulenburg V, Gomeza J. Inactivation of the Mouse L-Proline Transporter PROT Alters Glutamatergic Synapse Biochemistry and Perturbs Behaviors Required to Respond to Environmental Changes. Front Mol Neurosci. 2018 Aug 20;11:279. doi: 10.3389/fnmol.2018.00279. eCollection 2018.

Serpa Neto A, Juffermans NP, Hemmes SNT, Barbas CSV, Beiderlinden M, Biehl M, Fernandez-Bustamante A, Futier E, Gajic O, Jaber S, Kozian A, Licker M, Lin WQ, Memtsoudis SG, Miranda DR, Moine P, Paparella D, Ranieri M, Scavonetto F, Schilling T, Selmo G, Severgnini P, Sprung J, Sundar S, Talmor D, Treschan T, Unzueta C, Weingarten TN, Wolthuis EK, Wrigge H, de Abreu MG, Pelosi P, Schultz MJ; PROVE Network Investigators. Interaction between peri-operative blood transfusion, tidal volume, airway pressure and postoperative ARDS: an individual patient data meta-analysis. Ann Transl Med 2018; 6(2): 23.

Simonis FD, Barbas CSV, Artigas-Raventós A, Canet J, Determann RM, Anstey J, Hedenstierna G, Hemmes SNT, Hermans G, Hiesmayr M, Hollmann MW, Jaber S, Martin-Loeches I, Mills GH, Pearse RM, Putensen C, Schmid W, Severgnini P, Smith R, Treschan TA, Tschernko EM, Vidal Melo MF, Wrigge H, de Abreu MG, Pelosi P, Schultz MJ, Neto AS; PRoVENT investigators; PROVE Network investigators. Potentially modifiable respiratory variables contributing to outcome in ICU patients without ARDS: a secondary analysis of PRoVENT. Ann Intensive Care 2018; 8(1): 39.

Struck MF, Ewens S, Fakler JKM, Hempel G, Beilicke A, Bernhard M, Stumpp P, Josten C, Stehr SN, Wrigge H, Krämer S. Clinical consequences of chest tube malposition in trauma resuscitation: single-center experience. Eur J Trauma Emerg Surg. 2018 May 31. doi: 10.1007/s00068-018-0966-z.

Struck MF, Fakler JKM, Bernhard M, Busch T, Stumpp P, Hempel G, Beilicke A, Stehr SN, Josten C, Wrigge H. Mechanical complications and outcomes following invasive emergency procedures in severely injured trauma patients. Sci Rep 2018; 8(1): 3976.

Struck MF, Ewens S, Schummer W, Busch T, Bernhard M, Fakler JKM, Stumpp P, Stehr SN, Josten C, Wrigge H. Central venous catheterization for acute trauma resuscitation: Tip position analysis using routine emergency computed tomography. J Vasc Access 2018; doi: 10.1177/1129729818758998. [Epub ahead of print]

Tantra M, Guo L, Kim J, Zainolabidin N, Augustine GJ, Eulenburg V, Chen AI. Conditional Deletion of Cadherin-13 Perturbs Golgi Cells and Disrupts Social and Cognitive Behaviors. Genes Brain Behav 2018; doi: 10.1111/gbb.12466. [Epub ahead of print]

van Haren F, Pham T, Brochard L, Bellani G, Laffey J, Dres M, Fan E, Goligher EC, Heunks L, Lynch J, Wrigge H, McAuley D; and the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) and the ESICM Trials Group (Wrigge H, Reske AW, Simon P). Spontaneous Breathing in Early Acute Respiratory Distress Syndrome: Insights From the Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE Study. Crit Care Med. 2018 Oct 30. doi: 10.1097/CCM.0000000000003519.

Voelker MT, Bergmann A, Busch T, Jahn N, Laudi S, Noreikat K, Simon P, Bercker S. The effects of hemoglobin glutamer-200 and iNO on pulmonary vascular tone and arterial oxygenation in an experimental acute respiratory distress syndrome. Pulm Pharmacol Ther 2018; 49: 130-133.

Voelker MT, Wiechmann M, Dietz A, Laudi S, Bercker S. Two-Year Follow-Up After Percutaneous Dilatational Tracheostomy in a Surgical ICU. Respir Care. 2017 Jul;62(7):963-969.

Vogelsang M, Rockenbauch K, Wrigge H, Heinke W, Hempel G. Medical Education for "Generation Z": Everything online?! - An analysis of Internet-based media use by teachers in medicine. GMS J Med Educ. 2018 May 15;35(2):Doc21.

Wichmann G, Herchenhahn C, Boehm A, Mozet C, Hofer M, Fischer M, Kolb M, Dietz A. HLA traits linked to development of head and neck squamous cell carcinoma affect the progression-free survival of patients. Oral Oncol. 2017 Jun;69:115-127.

Wichmann G, Lehmann C, Herchenhahn C, Kolb M, Hofer M, Wiegand S, Dietz A. Development of a Human Leukocyte Antigen Score to Predict Progression-Free Survival in Head and Neck Squamous Cell Carcinoma Patients. Front Oncol. 2018 May 17;8:168.



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